What are the causes of hereditary diabetes?

Diabetes etiology and pathogenesis is very complex, has not yet fully elucidated, the traditional doctrine that the following factors: genetic factors recognized in the world, diabetes is a genetic disease, genetic research shows that the incidence of diabetes in the blood relatives and non-blood relatives Significant differences, the former than the latter 5 times higher. In the etiology of type 1 diabetes, the importance of genetic factors is 50%, and in diabetes type Ⅱ, the importance of more than 90%, so the cause of diabetes type Ⅱ genetic factors were significantly higher than diabetes type Ⅰ. With the deepening of diabetes research and understanding, from the molecular biology, electron microscopy ultrastructure, immunology, physiology and biochemistry and other multi-angle control of the cause of diabetes and the pathogenesis of a new understanding. Genetic factors are currently considered that diabetes is caused by several genetic damage: type 1 diabetes mellitus & mdash; & mdash; human sixth pair of chromosome short arm HLA-D gene damage; type 2 diabetes & mdash; insulin gene, insulin Receptor gene, glucosease gene and mitochondrial gene damage.

Symptoms of Diabetes
Diabetes is a typical symptom of "more than three less", that is, drink, polyuria, eat and lose weight. However, due to the severity of the disease or the different ways of disease, not every patient has these symptoms.
Polyuria: increased urine output per day and night urine volume of 3000 to 5000 ml, up to 10,000 ml or more. The number of urination also increased, one or two hours may be urine 1, and some patients even up to 30 times every day and night. Diabetic blood glucose levels increased, the body can not be fully utilized, especially the glomerular filtration and can not be completely reabsorbed by the renal tubules, resulting in the formation of osmotic diuretic, polyuria. The higher the blood sugar, the more urine is discharged, the more urine output.