What is the cause of diabetes?
Diabetes is a very common middle-aged and old disease, in recent years, with the lifestyle changes, middle-aged increase in the proportion of diabetes, because it is a very dangerous body of the patient's disease, so be sure to Attention to the prevention of diabetes. Here the specific cause of diabetes to introduce:
The etiology of diabetes
Diabetes Etiology 1, Obesity
This is an important environmental factor in the development and progression of non-insulin-dependent diabetes mellitus. The number of insulin receptors in obese adipose cells is reduced, the affinity for insulin is reduced, the degree of obesity and the duration of obesity can affect the appearance of hyperglycemia. The heavier the degree of obesity, the longer the duration, the more prone to diabetes.
Diabetes Etiology 2, autoimmune
Autoimmune is mainly the cause of type I diabetes. Diabetic patients are often accompanied by autoimmune diseases such as pernicious anemia, hyperthyroidism, Hashimoto's thyroiditis and myasthenia gravis.
Diabetes cause 3, excessive insulin
Under normal circumstances, pancreatic islet B cells secrete insulin containing about 5% of insulin. However, due to the mutation of insulin gene, a large number of proinsulin can not be converted into insulin and into the blood circulation, so the test showed hyperinsulinemia. Clinical manifestations of impaired glucose tolerance or non-insulin-dependent diabetes mellitus.
Diabetes cause 4, neurological factors
For decades, Chinese and foreign scholars believe that: the spirit of tension, emotional fluctuations and sudden trauma, etc., can cause increased blood sugar hormone secretion increased. These hormones are also hormones that fight against insulin, and thus raise blood sugar.
Diabetes mellitus 5, target cell receptor deficiency
Insulin action of the target cells are mainly liver cells, adipocytes, muscle cells, blood cells, lung and kidney cells, testicular cells and so on. Insulin at the cellular level play a physiological role, must be combined with the target cell insulin receptor, in order to affect the synthesis of intracellular material and metabolism. This is a prerequisite for normal physiological action of insulin. But when the number of receptors is reduced, the affinity of the receptor in combination with insulin is reduced, and insulin can not play a normal role, and blood glucose levels may rise.
It must be noted that the genetic factors of diabetes is very obvious, diabetes is divided into two types, but these two types have more obvious genetic characteristics, so that people with a family history of diabetes, we must pay attention to Prevention of diabetes.
The etiology of diabetes
This is an important environmental factor in the development and progression of non-insulin-dependent diabetes mellitus. The number of insulin receptors in obese adipose cells is reduced, the affinity for insulin is reduced, the degree of obesity and the duration of obesity can affect the appearance of hyperglycemia. The heavier the degree of obesity, the longer the duration, the more prone to diabetes.
Diabetes Etiology 2, autoimmune
Autoimmune is mainly the cause of type I diabetes. Diabetic patients are often accompanied by autoimmune diseases such as pernicious anemia, hyperthyroidism, Hashimoto's thyroiditis and myasthenia gravis.
Diabetes cause 3, excessive insulin
Under normal circumstances, pancreatic islet B cells secrete insulin containing about 5% of insulin. However, due to the mutation of insulin gene, a large number of proinsulin can not be converted into insulin and into the blood circulation, so the test showed hyperinsulinemia. Clinical manifestations of impaired glucose tolerance or non-insulin-dependent diabetes mellitus.
Diabetes cause 4, neurological factors
For decades, Chinese and foreign scholars believe that: the spirit of tension, emotional fluctuations and sudden trauma, etc., can cause increased blood sugar hormone secretion increased. These hormones are also hormones that fight against insulin, and thus raise blood sugar.
Diabetes mellitus 5, target cell receptor deficiency
Insulin action of the target cells are mainly liver cells, adipocytes, muscle cells, blood cells, lung and kidney cells, testicular cells and so on. Insulin at the cellular level play a physiological role, must be combined with the target cell insulin receptor, in order to affect the synthesis of intracellular material and metabolism. This is a prerequisite for normal physiological action of insulin. But when the number of receptors is reduced, the affinity of the receptor in combination with insulin is reduced, and insulin can not play a normal role, and blood glucose levels may rise.
It must be noted that the genetic factors of diabetes is very obvious, diabetes is divided into two types, but these two types have more obvious genetic characteristics, so that people with a family history of diabetes, we must pay attention to Prevention of diabetes.
评论
发表评论